HOW CAN WE HELP YOU? Call 1-800-TRY-CHOP
In This Section
Stephanie Hurwitz, MD, PhD, is a research fellow focused on improving understanding of the molecular biogenesis and functions of extracellular vesicles in physiologic and regenerative hematopoietic stem cell biology.
Stephanie Hurwitz, MD, PhD, is a physician-scientist and research fellow in the Kurre Laboratory, and a Hematopathologist at the University of Pennsylvania. She obtained her MD and PhD degrees from the Florida State University College of Medicine before completing Clinical Pathology residency and Hematopathology fellowship training at the University of Pennsylvania. She has expertise in extracellular vesicles (EVs), a diverse population of secreted vesicles that contain biologically active cargo and mediate numerous forms of cell-cell communication. Her work has contributed to further dissecting molecular mechanisms of EV biogenesis, and developing novel and robust vesicle isolation techniques for comprehensive characterization.
In the bone marrow, secreted EVs regulate cellular homeostasis and facilitate bidirectional cell-cell communication. Dr. Hurwitz's research in the Kurre Laboratory is centered on investigating crucial factors in the biogenesis of EVs derived from hematopoietic stem and progenitor cells and the roles of secreted vesicles in modulating steady-state and regenerative hematopoiesis. As a physician-scientist, she is interested in advancing understanding of homeostatic hematopoiesis and informing potential strategies for improving hematopoietic stem cell transplantation outcomes.