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Mustafa Mir, PhD
Mustafa Mir, PhD
Principal Investigator

Dr. Mir develops and applies advanced fluorescence microscopy and single molecule imaging methods to study the dynamics of nuclear organization and transcriptional regulation during early embryonic development.

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Education and Training

PhD, Electrical Engineering, University of Illinois at Urbana-Champaign, 2013

MSc, Electrical Engineering, University of Illinois at Urbana-Champaign, 2010

BS, Electrical Engineering, University of Illinois at Urbana-Champaign, 2008

Titles and Academic Titles

Principal Investigator

Assistant Professor in the Center for Computational and Genomic Medicine at Children’s Hospital of Philadelphia

Department of Cell and Developmental Biology at the University of Pennsylvania

Publication Highlights

Chong S, Mir M. Towards decoding the sequence-based grammar governing the functions of intrinsically disordered protein regions. J Mol Biol. 2020 Nov; [Online ahead of print]. PMID: 33248138.
McSwiggen DT, Mir M, Darzacq X, Tjian R. Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences. Genes Dev. 2019 Dec; 33(23-24):1619-1634. PMID: 31594803
Mir M, Bickmore W, Furlong EEM, Narlikar GJ. Chromatin topology, condensates, and gene regulation: shifting paradigms or just a phase?. Development. 2019 Sep; 146(19):dev182766. PMID: 31554625
Mir M, Stadler MR, Ortiz SA, Darzacq X, Eisen MB. Dynamic multifactor hubs transiently interact with sites of active transcription in Drosophila embryos. eLife. 2018 Dec; e40497. PMID: 30589412
Mir M, Reimer A, Stadler M, Tangara A, Hansen AS, Hockemeyer D, Eisen MB, Garcia H, Darzacq X. Single molecule imaging in live embryos using lattice light-sheet microscopy. Methods Mol Biol. 2018 Jan; 1814:541-559. PMID: 2995654