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Dr. Ma focuses on immune engineering. He leverages genetic, chemistry, and engineering tools to dissect immune cell-cell and cell-tissue crosstalk and harness these crosstalk mechanisms to develop biomaterials, protein, and cell-based precision immunotherapies for cancer and autoimmune diseases.
Advances the Research Institute’s commitment to the development of shared resources that facilitate interdisciplinary research through numerous Core facilities that service both laboratory and clinical research programs.
Dr. MacFarland's research focuses on syndromes that predispose to cancer development in children and adolescents. She has initiated several individual and collaborative research projects, working in pediatric polyposis syndromes and Li-Fraumeni syndrome. She is uncovering novel genomic drivers of disease and identifying biomarkers of cancer onset and progression.
Dr. Manirque Espinel is an attending anesthesiologist in the Division of Cardiothoracic Anesthesiology at CHOP and a professor of Clinical Anesthesiology and Critical Care at the Perelman School of Medicine of the University of Pennsylvania. Her research focuses on pediatric anesthesiology.
Dr. Margaritis uses biochemical, molecular, and complex in vivo methodology within the field of coagulation to advance the understanding of molecular mechanisms involved in pro- and anti-coagulant reactions, and translate research for the treatment of coagulation defects.
Dr. Maris investigates the molecular and genetic mechanisms contributing to the development and progression of neuroblastoma, a common childhood cancer. He also aims to develop new molecular diagnostic tests and less toxic, targeted therapies to treat relapsed or refractory neuroblastoma, including a major effort in immunotherapy discovery and development.
Dr. Marks investigates the molecular mechanisms underlying the formation of cell type-specific lysosome-related organelles; the assembly, delivery and function of their contents; and how these processes are impacted by genetic diseases.
Dr. Marsh's research program focuses on understanding how changes in brain development lead to epilepsy, intellectual disability, and autism. He combines molecular and physiological tools in mouse models to ask questions about the interaction of normal development with single gene mutations to determine how the brain responds to perturbations in development.
Dr. Mascarenhas is director of the Nutrition Support Service, section chief of nutrition in the Division of Gastroenterology and Nutrition, medical director of the Clinical Nutrition Department, and director of the Integrative Health Program. Her research interests involve 22q deletion syndrome, cystic fibrosis, nutrition, and integrative medicine.
Dr. Master studies pediatric and adolescent concussions and identifies interventions that improve time to recovery and clinical outcomes. In particular, she is interested in visual and vestibular problems that occur after concussion that may contribute to persisting prolonged symptomatology and impaired function and the role they play as targets for active intervention.
Dr. Master works to understand the biochemical pathways related to inborn errors of metabolism, particularly as they relate to mitochondrial function. He also focuses on bioinformatics and machine learning solutions to problems in mass spectrometry and laboratory medicine.
Dr. Mattei is an attending physician in the Division of General, Thoracic and Fetal Surgery and specializes in pediatric surgical oncology, inflammatory bowel disease, and minimally invasive and robotic surgery. His research interests are in oncology and IBD.
Dr. Maude focuses on novel therapies for high-risk and relapsed pediatric acute lymphoblastic leukemia (ALL). She aims to identify new pediatric ALL treatments that are more effective, less toxic, and exhibit fewer side effects than existing cancer therapies.
Dr. Mautone's research focuses on assessment and treatment of attention-deficit/hyperactivity disorder. She has expertise in family-school-health system collaboration, classroom consultation, and integrated behavioral health in primary care settings. She has a special interest in increasing access to high-quality, culturally competent care for underserved children and families.
Dr. Mayne is an epidemiologist whose research focuses on preventing cardiovascular disease and promoting healthy behaviors in children and their families. She employs multilevel and longitudinal methods to study how factors at the individual, family, neighborhood, and policy level influence risk factor behaviors and cardiometabolic outcomes. She is also engaged in research to promote innovation in pediatric primary care.
Dr. McCormack investigates the intersection of neuroendocrinology and metabolism. Her translational research program involves two areas. The first involves studying those with genetic disorders, including primary mitochondrial diseases and Friedreich's ataxia, with characterized risk for diabetes mellitus. Second, Dr. McCormack focuses on brain disorders associated with excess weight gain, including brain tumor-related hypothalamic obesity syndrome and idiopathic intracranial hypertension.
As the research nurse coordinator at PeRC, McGoldrick understands each of the Kid’s First and Primary Care Centers’ individual operating practices and their needs in contributing to research initiatives as a part of the PeRC team.
Dr. McGrath-Morrow is associate chief of the Division of Pulmonary and Sleep Medicine and leader of the Post-preemie Lung Disease Clinic at Children’s Hospital of Philadelphia. Her research seeks to link early life events with adult lung health and biomarker discovery for future trials.
Dr. Merves has a background in basic and clinical translational research in eosinophilic esophagitis. Her more recent focus is clinical research in the pediatric short-bowel population. Dr. Merves is currently evaluating blenderized feeding in the pediatric short bowel population.
Dr. Madelilne Miano is an attending anesthesiologist at Children's Hospital of Philadelphia, and assistant professor of Clinical Anesthesiology and Critical Care at the Perelman School of Medicine of the University of Pennsylvania. Her research focuses on pediatric anesthesiology.
Dr. Miller conducts developmentally informed behavioral research to examine the impact of parent-youth communication and decision making on health-related behaviors and outcomes. She aims to conduct research that facilitates youth involvement and empowerment in health-related decision making and enhances parent-youth-provider relationships.
Dr. Miller's research focuses on diagnostic and outcome issues, including differentiating autism from other genetic and psychiatric conditions, diagnostic and outcome studies across the lifespan, early identification and screening, and improving systems of care.
Dr. Mitchell's research aims to explain variations in childhood growth patterns related to the causes and prevention of diseases in later life. This includes studying the impact of behaviors and genes on body composition during development, especially childhood sleep and physical activity behavior.
Dr. Mollen's research career has been focusing on using non traditional setting as sites for interventions to improve adolescent reproductive health. She founded and oversees a research program in Children's Hospital of Philadelphia's Emergency Department that provides sexual health education and HIV testing services, and explores intervention opportunities for increasing access to reproductive health services in the ED.
Dr. Monos is an internationally recognized expert on histocompatibility (HLA) molecules. His work covers a wide spectrum of HLA-related issues that pertain to both the molecular (structure/function) aspects of HLAs, as well as the genetics of the major histocompatibility complex, that includes the genes encoding the HLA molecules.