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Heuckeroth Laboratory Publications

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Below is a list of selected publications from Heuckeroth Laboratory:

Pseudo-obstruction inducing ACTG2 R257C alters actin organization and function
JCI Insight · August, 2021
Cell-autonomous retinoic acid receptor signaling has stage-specific effects on mouse enteric nervous system
JCI Insight · May, 2021
Sympathetic input to multiple cell types in mouse and human colon produces region-specific responses
Gastroenterology · March, 2021
Glial Cell Derived Neurotrophic Factor Induces Enteric Neurogenesis and Improves Colon Structure and Function in Mouse Models of Hirschsprung Disease
Gastroenterology · July, 2020
Robust, 3-Dimensional Visualization of Human Colon Enteric Nervous System Without Tissue Sectioning
Gastroenterology · June, 2020
The EXTrauterine Environment for Neonatal Development Supports Normal Intestinal Maturation and Development
Cell Mol Gastroenterol Hepatol · May, 2020
Dlx1/2 mice have abnormal enteric nervous system function
JCI Insight · February, 2020
Down syndrome mouse models have an abnormal enteric nervous system
JCI insight · April, 2019
Loss of Tbx3 in murine neural crest reduces enteric glia and causes cleft palate, but does not influence heart development or bowel transit
Dev Biol · December, 2018
Muscularis macrophage development in the absence of an enteric nervous system
Proc Natl Acad Sci U.S.A · May, 2018
Neural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeleton
Dev Biol · January, 2016
Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse
Dev Biol · January, 2016
Hepatocyte Growth Factor and MET Support Mouse Enteric Nervous System Development, the Peristaltic Response, and Intestinal Epithelial Proliferation in Response to Injury
J Neurosci · August, 2015
Vascular and neural stem cells in the gut: do they need each other?
Histochem Cell Biol · April, 2015
Building a second brain in the bowel
J Clin Invest · March, 2015
Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis
J Clin Invest · November, 2013
Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function
Dev Biol · September, 2013
Enteric nervous system development, migration, differentiation and disease
Am J Physiol Gastrointest Liver Physiol · July, 2013
Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction
J Clin Invest · January, 2013
Ret heterozygous mice have enhanced intestinal adaptation after massive small bowel resection
Am J Physiol Gastrointest Live Physiol · May, 2012