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Division of Urology
Research in the Division of Urology bridges the connection between laboratory-based and clinical studies as investigators continue to study the uroscience of voiding function and dysfunction.
Investigators conducting laboratory-based research seek to understand the ways in which human brains and bladders connect, with an eye toward developing new ways to treat voiding dysfunction. This approach involves mastering the application of the new technique of optogenetics and screening potential genotypes to find those that show changes in bladder function or size. In addition, researchers are developing a real-time uroflometry system for home use that can drive its data to technologies like smart phones and EPIC.
The Division of Urology's clinical research program encompasses prospective randomized clinical trials, prospective observational studies, clinical studies on patient care, multi-institutional studies and internal collaborative research programs. All of the Division's clinical research projects and programs seek to develop innovative ways to treat complex urological conditions seen in the investigators’ clinics.
Examples of current clinical research studies involve magnetoencephalography and bladder volume responsive zones of the cerebral cortex; congenital and acquired urologic conditions; iPhone/iPad-based uroflow system for interactive biofeedback; bladder exstrophy; gut microbiome and kidney stone disease; biomarker identification in chronic kidney disease; the association between dietary fructose, zinc, and kidney stones; and robotic-assisted laparoscopic heminephrectomy versus robotic-assisted laparoscopic ureteroureterostomy.