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CCCR Research Studies
1 - 10 of 31
22LL011; Epcoritamab in B-cell Neoplasms
CHOP in collaboration with AbbVie, is conducting a study for pediatric patients from 1 year of age to 25 years of age with relapsed or refractory aggressive mature B-cell neoplasms (including diffuse large B-cell lymphoma, Burkitt and Burkitt-like lymphoma/leukemia).
AALL2121: SNDX-5613 for Relapsed or Refractory Leukemia
This study enrolls patients that have been diagnosed with acute leukemia associated with a KMT2A (MLL) gene rearrangement (referred to as KMT2Arearranged, or KMT2A-R).
AAML1921; Bosutinib for Chronic Myeloid Leukemia
The overall goals of this study are to find the best dose of bosutinib that we can give safely, and to find out what effects, good and/or bad, bosutinib has on children and adolescents with Chronic Myeloid Leukemia (CML).
ABA3 GVHD ProRx post Allo HACT
This study involves taking the study drug, abatacept, by intravenous (IV) infusion.Alpelisib in PIK3CA-related overgrowth syndrome
The purpose of this study is to find out if alpelisib (BYL719; the “study drug”), is safe and effective (can help) people who have PIK3CA-related overgrowth spectrum (PROS) disease.
BA3011 for advanced solid tumors
This study involves taking a study drug called BA3011. The overall goal of this study is to see if BA3011 is a possible treatment for patients with sarcoma.
Cabo/Ifos in Ewing Sarcoma and Osteosarcoma
This study enrolls patients between 5 and 40 years of age with a diagnosis of Ewing sarcoma (including Ewing-like sarcoma) or osteosarcoma that has progressed on or relapsed after upfront initial therapy.
Cancer Genomic Testing Study
The Department of Genomic Diagnostics is interested in studying genetic/molecular testing results from patients who are diagnosed with cancer as confirmed by genetic testing done at CHOP.
Carfilzomib in ALL
This clinical trial is adding the study drug, Carfilzomib, to a standard relapse chemotherapy regimen.
Chemotherapy-induced Nausea and Vomiting Control
The overall goal of this study is to find the best strategies used by parents and patients for managing these symptoms when receiving maintenance therapy.