This week, new research findings at Children's Hospital of Philadelphia are propelling the way we think about autism, single ventricle survivors, and neuroblastoma forward.
Melding together genomics technology, disease patterns, immunology, and microbiology, physician-scientists at The Children’s Hospital of Philadelphia are finding new and individualized therapies for patients with very early onset inflammatory bowel disease.
In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child’s need for pain-control drugs.
A new study detailing the largest-ever genetic analysis of blood pressure in African Americans has identified five gene variants linked to the trait. According to the study, which was published recently in the American Journal of Human Genetics, three of the gene variants have not previously been implicated in blood pressure, and represent novel findings.
Dr. Hakonarson, director of the Center for Applied Genomics at Children's Hospital, led the study, which is the first to look at copy variation numbers in children that may be linked with human lifespan. Several gene variants can influence a person's potential lifespan by either raising the probability of developing a disease or by providing protection from disease, according to new
