The efforts of the Hospital's research community are supported by an administrative infrastructure provided by the Children's Hospital of Philadelphia Research Institute. This infrastructure provides operational, financial, managerial, human resources, compliance, and training support to investigators, and provides the framework for compliance with the myriad requirements governing research.
Here are our current Administrative Units:
Clinical and Translational Research
Clinical and translational research are critical components for the success of the mission of the CHOP Research Institute and Children's Hospital. Such research is needed to ensure that the rapid advances in biomedical sciences can be efficiently moved into patient-oriented research in a scientifically rigorous, pediatric centric manner. The Office of Clinical and Translational Research (OCTR), works with investigators from across the spectrum of our scientific community to focus efforts and resources for this growing research discipline.
The OCTR assists clinical and translational investigators in identifying scientific opportunities and in forging productive collaborations throughout the Hospital and the University of Pennsylvania. With the increasing complexities involved in conducting clinical and translational research, the OCTR develops and implements improvements in the clinical and administrative research infrastructure, including working with the leaders of the Committee for the Protection of Human Subjects, the Office of Research Compliance, the Clinical and Translational Research Center and the Clinical Research Support Office (CRSO) to support investigators in their efforts to translate laboratory advances to the clinic and back again to the bench.
Clinical Trials Financial Management
The Clinical Trials Financial Management office provides a range of financial management services to the research community at Children's Hospital. The team assists principal investigators, hospital administrators, and study coordinators by serving as a resource in the areas of patient care cost management, budget preparation, research subject registration, patient scheduling, research charge review, reconciliation, sponsor invoicing, and grant close outs.
Clinical Research Support Office
The Clinical Research Support Office (CRSO) assists in the start-up, execution, and completion of clinical research projects, in compliance with local and federal requirements. The CRSO offers comprehensive support to clinical research investigators and is comprised of a staffing core, clinical trial contracting, recruitment enhancement, IND/IDE support, and a research navigator. The Clinical Trials Financial Management (CTFM) department reports up through the CRSO now as well.
- The Research Staffing Core consists of well-trained research assistants, study coordinators, nurses, and project/program managers who can be assigned, full- or part-time, to support any type of clinical research study at Children's Hospital. All staff are assigned a team manager to provide additional support to staff and their investigators.
- CRSO Contract Administrators negotiate industry-sponsored agreements.
- CRSO Recruitment Enhancement Core (REC) assists investigators and research teams in planning, developing, and executing effective recruitment and retention strategies with the goal of making it easier to meet established enrollment goals.
- The IND/IDE Support Program provides regulatory guidance, operational support, and institutional oversight for all CHOP Investigator-held Investigational New Drug (IND)/Investigational Device Exemption (IDE) research. Additional services include Sponsor-Investigator responsibilities training, workshops, lectures, and available tools and templates for the conduct of Sponsor-Investigator research.
- Michele Toms, Administrative Director, Clinical Research Staffing Core
- Phone: 215-590-7727
- Kristina Harr, JD, Administrative Director, OnCore/REDCap
- Phone: 267-426-8193
- Richard Aplenc, MD, PhD, MSCE, Assistant Vice President and Chief Clinical Research Officer
- Phone: 267-426-7252
The CRSO works with faculty on industry- and investigator-initiated clinical research and facilitates contact between principal investigators and sponsors or contract research organizations interested in conducting trials at the Hospital.
Research Communications describes and promotes the Institute and its research both internally and externally. The department maintains the Institute’s blog, manages social media, works to enhance media exposure, publishes research news through a variety of publications, manages branding for the Research Institute, communicates with investigators and research staff, maintains Web content and provides a multitude of other services to investigators, staff and administration.
Core Facility Administration
Core Facility Administration oversees the administrative and financial operation of scientific core facilities at the Children's Hospital of Philadelphia Research Institute. These activities include setting institutional cores' strategic directions and priorities; coordinating the planning and marketing efforts of the cores; maintaining internal and external core communications; developing and monitoring core pricing and budgets; and reporting metrics and benchmarks for each core.
Facilities and Resources
Research Resources partners with faculty and staff to establish the physical infrastructure required to support the research enterprise. These efforts include managing major capital construction, minor renovation projects as well as coordinating the relocation of research programs. Research Resources provides a single point for contact for faculty and staff to request services from Hospital support service groups. The department also manages strategic and long-range planning, assessment of research space utilization and works with the research finance department to coordinate inventory of capital equipment.
The Office of Faculty Development designs workshops, workshop series, and conferences to support the success and satisfaction of University of Pennsylvania School of Medicine-based CHOP faculty. The office also serves as a central clearinghouse for information on professional development opportunities and resources available at Children's Hospital, the University of Pennsylvania, it’s school of medicine, and external institutions and professional organizations such as the Association of American Medical Colleges. The office also honors outstanding faculty mentors of other faculty at the hospital through an annual Mentor Award.
Research Finance coordinates the financial activities of The Children's Hospital of Philadelphia Research Institute in compliance with institutional and sponsor policies. This group is responsible for accounting, financial administration, planning, internal and external reporting and establishment of financial policies and procedures. Finance also coordinates audits, ensures compliance with federal cost principles, assists investigators with closing out sponsored projects, and maintains responsibility for budgeting and monitoring the research institute's financial position.
Research Human Resources is a joint unit of Hospital Human Resources and the CHOP Research Institute that specializes in recruiting research personnel and designing and developing goals that align with the Institute's strategic and operational plans and goals.
As The Children's Hospital of Philadelphia Research Institute continues to prepare for upcoming recruitment efforts and growth, Research Human Resources continues to seek ways to attract qualified candidates and trainees. To find out about our current openings in research, please visit the careers page on this site. More information about our postdoctoral fellowship opportunities is available on this site's postdoc pages.
Human Subjects Research
Human Subjects Research is responsible for maintaining the infrastructure required to support the Hospital's Institutional Review Board (IRB) committees including electronic systems, budget and financial tracking. The department implements and maintains all IRB management systems, and trains IRB staff, investigators and study coordinators. Human Subjects Research also collaborates with other departments to ensure that IRB policies and procedures, educational activities and operational systems enable the IRB's and Hospital's human subjects protection programs to function effectively.
Research Information Systems, a joint unit of Hospital Information Systems and the CHOP Research Institute, serves the unique computing needs of the scientific community. The department provides on-site technical support for research, implements policies for specialized research information technology support and provides capabilties and expertise for advanced scientific computing for research.
Office of Academic Training and Outreach Programs
The Office of Academic Training and Outreach Programs is dedicated to supporting the next generation of scientists by improving the research trainee experience, management of research training requirements, STEM pipeline programming, and diversity support programming at the Children's Hospital of Philadelphia. The office serves as a central resource for trainees, providing programmatic support to all research trainees (including postdoctoral fellows, MD fellows, training grant fellows and CHOP-based UPenn graduate students) and maintaining a specialized administrative infrastructure to support the Children's Hospital of Philadelphia postdoc population.
Office of Collaborative and Corporate Research Contracts
The Office of Collaborative and Corporate Research Contracts, or OCCRC, was created in 2018 as a single entrance point for CHOP faculty and staff to initiate agreements with both industry and academic partners. Consisting of the contracting groups previously housed within the Office of Technology Transfer and the Clinical Research Support Office, OCCRC negotiates contracts where CHOP is receiving funds from industry sponsors for both research and clinical trials, as well as the various non-funded agreements that support the faculty’s research efforts, such as Non-Disclosure Agreements, Data Use Agreements, and Material Transfer Agreements. Additionally, OCCRC provides cursory review of CHOP faculty private consulting agreements to ensure that their terms do not conflict with the researcher’s obligations to the Hospital.
If you are a CHOP employee:
- Click here to submit a request for an MTA, DUA, CDA, unfunded Collaboration Agreement, or CORE Services Agreement
- Click here to submit a request for a corporate Sponsored Research Agreement
- Click here to submit a CTA or CTA amendment
- Click here to submit a faculty consulting agreement
Office of Entrepreneurship & Innovation
The Office of Entrepreneurship & Innovation (OEI) works to create an entrepreneurial spirit throughout Children's Hospital. The Office is responsible for all entrepreneurial activities within CHOP and will accelerate CHOP's reputation as the leading center for entrepreneurship in pediatric medicine. This is accomplished by identifying potential spinouts, developing strategic partnerships, pursuing potential commercialization opportunities and developing early stage ideas, including innovative devices, therapies, mobile applications and software tools. OEI has created a centralized hub for managing existing and future entrepreneurial/innovation projects.
Office of Research Compliance and Regulatory Affairs
The Office of Research Compliance and Regulatory Affairs develops and maintains a comprehensive compliance program to enable the Children's Hospital of Philadelphia Research Institute to promote integrity and compliance throughout all research and sponsored programs.
- Matthew Hodgson, Assistant Vice President, Research Compliance and Regulatory Affairs
- Phone: 267-426-8723
- Karen Burke, Associate Director
- Phone: 267-425-2447
Office of Research Safety
The Office of Research Safety oversees the development, implementation and administration of biological, laboratory and chemical safety programs while working closely with Environmental Health and Safety for all Hospital-wide safety initiatives. The office partners with investigators and staff to develop policies and procedures that are relevant and practical and comply with government regulations. This office also administers the Institutional Biological Safety Committee.
Sponsored Projects and Research Business Management
To help CHOP investigators navigate the lifecycle of sponsored funding, Sponsored Projects and Research Business Management provides each with three key resources: their sponsored projects officer, contracting specialist, and their research business manager.
On the behalf of faculty, sponsored projects officers serve as CHOP's negotiators and advocates with funders and any other external entity sponsoring projects. They also guide researchers on application submissions, including progress reports, and are responsible for institutional sign-offs. Contracting specialists serve as CHOP's negotiators on incoming and outgoing sub-awards. Research business managers develop budgets and spending plans for faculty, in addition to providing account oversight, including cost monitoring, salary allocations, and project close-out. They serve as the researcher's financial advisors.
A joint unit of the Hospital's Supply Chain Department, The Children's Hospital of Philadelphia Research Institute's Supply Chain Department addresses the unique supply, instrumentation and contracting needs of research and ensures that the Hospital Supply Chain Department considers research-specific concerns. The Supply Chain Department ensures the timely delivery of the highest quality goods and services at the best overall cost to support the Hospital's research. The group assists divisions with expediting orders, processing returns and repairs and providing requested reports on purchased items. The department also administers price protection agreements by managing the bidding process, identifying bid opportunities and maintaining a bid cycle for routinely purchased items and services.
Office of Technology Transfer, Commercialization & Innovation
The Office of Technology Transfer protects, manages and maximizes the value of the Hospital's intellectual property by identifying and evaluating novel research discoveries that may be developed into commercial products, facilitating the intellectual property protection of discoveries through the patenting process, and working with inventors and commercial partners to introduce discoveries to the marketplace. Technology Transfer also oversees corporate-supported research collaborations, including clinical trial agreements, sponsored research agreements, as well as other research agreements for scholarly activities that have no funding attached (corporate or otherwise), such as confidential disclosure agreements, material transfer agreements, data use agreements, collaborative research agreements. In addition, the office works with Compliance related to the review of faculty consulting agreements. The group ensures that current and potential partners from the pharmaceutical, device, biotechnology and venture capital communities are aware of the Hospital's science and research activities, technologies available for licensing and opportunities for research collaboration and identifies sources for corporate-sponsored research and start-up company opportunities.